2-hydroxy-2-[(2-trifluoromethyl)phenyl]ethanamine

2-hydroxy-2-[(2-trifluoromethyl)phenyl]ethanamine - Names and Identifiers

Name	2-Amino-1-[2-(trifluoromethyl)phenyl]ethanol
Synonyms	AKOS BBV-002765 UKRORGSYN-BB BBV-002765 2-Amino-1-[2-(trifluoromethyl)phenyl]ethanol 2-amino-1-[2-(trifluoromethyl)phenyl]ethanol 2-amino-1-[2-(trifluoromethyl)phenyl]ethan-1-ol 2-hydroxy-2-[(2-trifluoromethyl)phenyl]ethanamine Benzenemethanol, α-(aminomethyl)-2-(trifluoromethyl)-
CAS	133562-36-4

2-hydroxy-2-[(2-trifluoromethyl)phenyl]ethanamine - Physico-chemical Properties

Molecular Formula	C9H10F3NO
Molar Mass	205.18
Density	1.301±0.06 g/cm3(Predicted)
Boling Point	292.6±35.0 °C(Predicted)
pKa	11.69±0.35(Predicted)
Storage Condition	Room Temprature

2-hydroxy-2-[(2-trifluoromethyl)phenyl]ethanamine - Introduction

2-Amino -1-[2-(trifluoromethyl) phenyl] ethanol is an organic compound with the chemical formula C9H10F3NO. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: It is a white crystalline solid.
-Melting point: Its melting point is about 92-94°C.
-Solubility: It can be dissolved in water and organic solvents.

Use:
- 2-Amino -1-[2-(trifluoromethyl) phenyl] ethanol is often used as a reagent in organic synthesis. It can be used as an amination reagent and an amine reagent.
-It can also be used in the field of medicine, such as the preparation of pharmaceutical raw materials.

Preparation Method:
2-Amino -1-[2-(trifluoromethyl) phenyl] ethanol can be synthesized by the following steps:
1. First, trifluoromethyl anisole (C8H7F3O) and bromoethanol undergo nucleophilic substitution reaction to generate 2-amino -1-[2-(trifluoromethyl) phenyl] ethanol bromide.
2. Next, the bromide is reacted with aqueous ammonia to produce 2-amino -1-[2-(trifluoromethyl) phenyl] ethanol.

Safety Information:
- 2-Amino -1-[2-(trifluoromethyl) phenyl] ethanol is less toxic, but it still needs to be handled with caution.
-During operation, wear appropriate protective equipment, such as lab gloves, goggles, etc.
-avoid contact with skin, eyes and respiratory tract, such as accidental contact, should immediately rinse with water.
-During storage and handling, avoid contact with oxidants, strong acids or alkalis, and avoid fire and high temperatures.
-Please follow the correct handling instructions and storage conditions to save and use the compound.

Last Update：2024-04-09 21:01:54